Often the question arises whether (Formula presented.) can be predicted based on (Formula presented.) using a certain model. Especially for highly flexible models such as neural networks one may ask whether a seemingly good prediction is actually better than fitting pure noise or whether it has to be attributed to the flexibility of the model. This paper proposes a rigorous permutation test to assess whether the prediction is better than the prediction of pure noise. The test avoids any sample splitting and is based instead on generating new pairings of (Formula presented.). It introduces a new formulation of the null hypothesis and rigorous justification for the test, which distinguishes it from the previous literature. The theoretical findings are applied both to simulated data and to sensor data of tennis serves in an experimental context. The simulation study underscores how the available information affects the test. It shows that the less informative the predictors, the lower the probability of rejecting the null hypothesis of fitting pure noise and emphasizes that detecting weaker dependence between variables requires a sufficient sample size.

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This multicenter observational study aimed to assess how pain reduction, induced by local anesthesia, affects the relative angular contributions of the shoulder girdle and trunk to the maximal angular performance during a semi-constrained overhead reach task in patients with ongoing shoulder pain. Twenty-nine individuals (age 59.0 SD 12.8 years;16-male) with symptomatic shoulders were administered corticosteroid and lidocaine injections by their attending orthopedic surgeon. Immediately before and after the injections, participants reached for a target on the ceiling ten times as high as possible while their pain levels, shoulder, and trunk movements were recorded. The analysis revealed that there was a significant reduction in pain following the injections. However, there were no significant differences in maximum shoulder and trunk inclination angles between the pre- and post-injection conditions. Notably, there were slight but statistically significant alterations in humeroscapular kinematics during the initial phase of arm elevation following the injections. In conclusion, acute pain relief following local anesthetics is not associated with immediate alterations in maximum shoulder girdle and trunk inclination angles during a semi-constrained overhead reach task in patients with ongoing shoulder pain. However, there are signs of small alterations in humeroscapular kinematics during the initial phase of arm elevation.

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CONTEXT: Baseball pitching requires fast and coordinated motions of the whole body to reach high ball speeds, putting considerable strain on the musculoskeletal system, particularly the shoulder and elbow. OBJECTIVE: To describe musculoskeletal symptoms and the functional status of the shoulder and elbow in male high school baseball pitchers. DESIGN: Descriptive epidemiology study. SETTING: Dutch baseball talent academies. PATIENTS OR OTHER PARTICIPANTS: One hundred twenty-five male high school baseball pitchers aged 12 to 18 years who participated in 1 of the 6 Dutch baseball talent academies and the Dutch National U-18 team were recruited and enrolled. MAIN OUTCOME MEASURE(S): Musculoskeletal symptoms, functional status of the shoulder and elbow were registered for each player every 6 months over 2 consecutive baseball seasons through self-assessment questionnaires, including the Kerlan-Jobe Orthopaedic Clinic (KJOC) and the Western Ontario Shoulder Instability Index (WOSI) questionnaires. RESULTS: Five hundred seventy musculoskeletal (MSS) symptoms in 93 of the 125 players were reported. The average 6-month prevalence for symptoms of the throwing shoulder was 37% (95% CI = 33%-41%), and for the elbow 37% (95% CI = 31%-42%), followed by the lower back with 36% (95% CI = 26%-45%). The baseball pitchers who experienced only shoulder symptoms had an average KJOC score of 80.0 (95% CI = 75.3-84.7) points, whereas those with only elbow symptoms reported a score of 90.2 (95% CI = 89.2-95.3). On the WOSI questionnaire, baseball pitchers scored an average of 421.2 (95% CI = 200.1-642.4) points. CONCLUSIONS: In a cohort of Dutch high school baseball pitchers, one-third reported shoulder and elbow symptoms on the throwing side, with reduced functional status and lower back symptoms. Future efforts should focus on developing preventive strategies through early symptom detection, aiming to prevent symptom progression and, ultimately, the development of severe injuries.

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In baseball pitchers the elbow is exposed to high and repetitive loads (i.e. external valgus torque), caused by pitching a high number of balls in a practice session or game. This can result in overuse injuries like the ulnar collateral ligament (UCL) injury. To understand injury mechanisms, the effect of repetitive pitching on the elbow load magnitude and variability was investigated. In addition, we explored whether repetitive pitching affects elbow muscle activation during pitching. Fifteen pitchers threw each 60 to 110 balls. The external valgus torque and electromyography of three elbow muscles were quantified during each pitch. Linear mixed model analyses were performed to investigate the effect of repetitive pitching. On a group level, the linear mixed models showed no significant associations of repetitive pitching with valgus torque magnitude and variability and elbow muscle activity. Significant differences exist between pitchers in their individual trajectories in elbow valgus torque and muscle activity with repetitive pitching. This shows the importance of individuality in relation to repetitive pitching. In order to achieve effective elbow injury prevention in baseball pitching, individual characteristics of changes in elbow load and muscle activity in relation to the development of UCL injuries should be investigated.

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Background: Baseball pitching performance can be mechanically explained by the summation of speed principle and the principle of optimal coordination of partial momenta. Impeding optimal energy generation or transfer by or between the pelvis and trunk segments could provide valuable insight into possible compensation or catch-up mechanisms that may manifest themselves based on these principles. Aim: The aim of the present study was to explore the effects of experimentally impeding the mobility of and between the pelvis and trunk segments (1) on ball speed and mechanical peak joint power, and (2) on mechanical peak load of the elbow and shoulder joints at maximal external rotation (MER) during fastball pitching. Methods: Eleven elite baseball pitchers (mean age 17.4, SD 2.2 years; mean pitching experience 8.9, SD 3.0 years) were instructed to throw at least 15 fastballs as fast and accurately as possible under two conditions. One condition involved impeding the mobility of the pelvis and trunk segments to hamper their ability to rotate independently, which consequently should affect the separation time, defined as the time interval between the pelvis and trunk peak angular velocities. In the other condition, pitchers threw unimpeded. Ball speed, mechanical peak joint power and peak net moment of the elbow and shoulder at MER were compared between conditions using Generalized Estimating Equations (GEE). Results: In the impeded pitching condition, the mean difference of the separation time was 12.4 milliseconds [95% CI (4.0, 20.7)] and for ball speed 0.6 mph [95% CI (0.2, 0.9)] lower compared to the unimpeded condition. Only the peak pelvic angular velocity, in addition to the trunk, upper arm and forearm, was 45 deg/s [95% CI (24, 66)] higher impeded condition. The mean differences of the joint power and net moments at the shoulder and elbow did not reach statistical significance. Conclusion: In elite adolescent baseball, the observed pitching performance after experimentally impeding pelvic and trunk mobility undermines a potential distal catch-up strategy based on the summation of speed principle. The increased peak pelvic angular velocity may indicate a compensation strategy following the optimal coordination of partial momenta principle to practically maintain pitching performance.

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Monitoring the performance and functional status of baseball pitchers’ upper extremity is important in maintaining the athlete’s health and performance. This study validated a Dutch translation of the original English Kerlan-Jobe Orthopaedic Clinic (KJOC) against the previously validated Disabilities of the Arm, Shoulder and Hand (DASH) and Western Ontario Shoulder Instability Index (WOSI) questionnaires in a group of talented juvenile Dutch baseball pitchers. Three times, from 2014–2016, 107 pitchers completed the Dutch KJOC, DASH and WOSI questionnaires. Participants’ questionnaire scores were analysed for the whole group and the symptomatic player subgroup separately. Internal consistency, construct validity and ceiling and floor effects were examined. Cronbach’s alpha was consistently above 0.8 for the three time periods for the whole group, and ranged between 0.62 and 0.86 for the symptomatic subgroup. Spearman’s rank correlation coefficients ranged from 0.47 to 0.67 for the whole group and 0.32 to 0.99 for the symptomatic subgroup. No floor effects were observed in the scores of the KJOC and only a ceiling effect for the whole group (15.2%) at one time period. The Dutch version of the KJOC has shown acceptable internal consistency and construct validity and can be used to assess overhead athletes’ shoulder and elbow functionality.

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The purpose of the present study was to investigate the effect of an experimentally imposed kinetic chain disturbance in baseball pitching on ball speed and elbow kinetics. The experimental design consisted of two (within-subject) conditions. In one condition there was no manipulation (control condition). The other condition involved a manipulation of the kinetic chain by taping the pelvis and trunk. In both conditions, pitchers were instructed to throw fastballs until a minimum of 15 pitches were captured. Inverse dynamic solutions were used calculate the internal elbow moments of six elite youth baseball pitchers. The pitchers that were hampered in throwing fastballs, by the taped pelvis and trunk, showed significant lower ball speeds and peak internal varus moments compared to the pitchers that were allowed to throw without any hindrance.
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Upper extremity injuries are common in baseball. One of these is the ulnar collateral ligament (UCL) injury. In the field of sports injuries, most research focuses on average kinematics and kinetics between subjects, whereas focusing on within-subject variability appears to be more relevant for determining injury risk. We constructed a simple explanatory simulation model to illustrate the relationship between within-subject load variability and risk, illustrating how pitchers with a higher load variability are more likely to sustain an injury compared to pitchers with less load variability. Furthermore, the model comprises the (theoretical) effect of fatigue on load variability and injury threshold over time.
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