T
TA Knijnenburg
21 records found
1
Regulatorynetworksareusuallypresentedasgraphstructuresshowingthe(combinatorial)regulatorye¿ectoftranscriptionfactors(TF¿s)onmodulesofsimilarlyexpressedorotherwiserelatedgenes.However,fromthesenetworksitisnotclearwhenandhowTF¿sareactivated.Theactualconditionsorperturbationsthattri
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Abstract
Markov blanket filtering based on discretized features (MBF) has been proposed as a feature selection strategy. Critical evaluation of MBF has demonstrated its contradictory and counterintuitive nature, which results in undesirable properties for small sample size applic
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When transcriptome meets metabolome
Fast cellular responses of yeast to sudden relief of glucose limitation.
Within the first 5 min after a sudden relief from glucose limitation, Saccharomyces cerevisiae exhibited fast changes of intracellular metabolite levels and a major transcriptional reprogramming. Integration of transcriptome and metabolome data revealed tight relationships betwee
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