Balance training aims to improve balance and transfer acquired skills to real-life tasks. How older adults adapt gait to different conditions, and whether these adaptations are altered by balance training, remains unclear. We hypothesized that reorganization of modular control of muscle activity is a mechanism underlying adaptation of gait to training and environmental constraints. We investigated the transfer of standing balance training, shown to enhance unipedal balance control, to gait and adaptations in neuromuscular control of gait between normal and narrow-base walking in twenty-two older adults (72.6 ± 4.2 years). At baseline, after one, and after ten training sessions, kinematics and EMG of normal and narrow-base treadmill walking were measured. Gait parameters and temporal activation profiles of five muscle synergies were compared between time-points and gait conditions. Effects of balance training and an interaction between training and gait condition on step width were found, but not on synergies. After ten training sessions step width decreased in narrow-base walking, while step width variability decreased in both conditions. Trunk center of mass displacement and velocity, and the local divergence exponent, were lower in narrow-base compared to normal walking. Activation duration in narrow-base compared to normal walking was shorter for synergies associated with dominant leg weight acceptance and non-dominant leg stance, and longer for the synergy associated with non-dominant heel-strike. Time of peak activation associated with dominant leg stance occurred earlier in narrow-base compared to normal walking, while it was delayed in synergies associated with heel-strikes and non-dominant leg stance. The adaptations of synergies to narrow-base walking may be interpreted as related to more cautious weight transfer to the new stance leg and enhanced control over center of mass movement in the stance phase. The improvement of gait stability due to standing balance training is promising for less mobile older adults.

@en

Training improves balance control in older adults, but the time course and neural mechanisms underlying these improvements are unclear. We studied balance robustness and performance, H-reflex gains, paired reflex depression, and co-contraction duration in ankle muscles after one and ten training sessions in 22 older adults (+65 yrs). Mediolateral balance robustness, time to balance loss in unipedal standing on a platform with decreasing rotational stiffness, improved (33%) after one session, with no further improvement after ten sessions. Balance performance, absolute mediolateral center of mass velocity, improved (18.75%) after one session in perturbed unipedal standing and (18.18%) after ten sessions in unperturbed unipedal standing. Co-contraction duration of soleus/tibialis anterior increased (16%) after ten sessions. H-reflex gain and paired reflex depression excitability did not change. H-reflex gains were lower, and soleus/tibialis anterior co-contraction duration was higher in participants with more robust balance after ten sessions, and co-contraction duration was higher in participants with better balance performance at several time-points. Changes in robustness and performance were uncorrelated with changes in co-contraction duration, H-reflex gain, or paired reflex depression. In older adults, balance robustness improved over a single session, while performance improved gradually over multiple sessions. Changes in co-contraction and excitability of ankle muscles were not exclusive causes of improved balance.

@en

Exoskeletons often allow limited movement of the ankle joint. This could increase the chance of falling while walking, particularly on challenging surfaces, such as lateral inclines. In this study, the effect of a mobility limiting ankle brace on gait stability in the frontal plane was assessed, while participants walked on lateral inclines. The brace negatively affected gait stability when it was worn on the leg that was on the vertically lower side or ‘valley side’ of the lateral incline, which would indicate an increased risk of falling in that direction.

@en

BACKGROUND: Literature describing differences in motor control between low back pain (LBP) patients and healthy controls is very inconsistent, which may be an indication for the existence of subgroups. Pain-related psychological factors might play a role causing these differences. PURPOSE: To examine the relation between fear of movement and variability of kinematics and muscle activation during gait in LBP patients. STUDY DESIGN: Cross-sectional experimental design. PATIENT SAMPLE: Thirty-one Chinese LBP patients. OUTCOME MEASURES: Self-report measures: Visual Analog Score for pain; TAMPA-score; Physiologic measures: electromyography, range of motion. FUNCTIONAL MEASURES: LBP history; the physical load of profession, physical activity. METHODS: Patients were divided in high and low fear of movement groups. Participants walked on a treadmill at four speeds: very slow, slow, preferred and fast. Kinematics of the thorax and the pelvis were recorded, together with the electromyography of five bilateral trunk muscle pairs. Kinematic and electromyography data were analysed in terms of stride-to-stride pattern variability. Factor analysis was applied to assess interdependence of 11 variability measures. To test for differences between groups, a mixed-design multivariate analysis of variance was conducted. RESULTS: Kinematic variability and variability of muscle activation consistently loaded on different factors and thus represented different underlying variables. No significant Group effects on variability of kinematics and muscle activation were found (Hotelling's Trace F=0.237; 0.396, p=.959;.846, respectively). Speed significantly decreased kinematic variability and increased variability in muscle activation (Hotelling's Trace F=8.363; 4.595, p<.0001; <.0001, respectively). No significant interactions between Group and Speed were found (Hotelling's Trace F=0.204; 0.100, p=.762;.963, respectively). CONCLUSIONS: The results of this study do not support the hypothesis that variability in trunk kinematics and trunk muscle activation during gait in LBP patients are associated with fear of movement.

@en

Purpose: The goal of this study was to assess differences in low back stabilization and underlying mechanisms between patients with low back pain (LBP) and healthy controls. It has been hypothesized that inadequate trunk stabilization could contribute to LBP through high tissue strains and/or impingement. Evidence to support this is inconsistent, and not all methods that have been used to study trunk stabilization are equally suitable. We have recently developed a method to assess intrinsic and reflexive contributions to trunk stabilization, which aims to circumvent the limitations of previous studies. Methods: Forty-nine participants suffering from chronic LBP and a control group of fifty healthy subjects participated in this study. Trunk stabilization was measured using force-controlled perturbations directly applied to the trunk. The actuator displacement and contact force between the actuator and subject were measured as well as electromyography (EMG) of the M. Longissimus. Underlying mechanisms were characterized using system identification. Results: LBP patients showed lower admittance, i.e., less displacement per unit of force applied, mainly due to higher position, velocity and acceleration feedback gains. Among patients, lower trunk admittance and higher reflex gains were associated with more negative pain-related cognitions. Conclusion: Trunk stabilization differs between LBP patients and controls, with the same perturbations causing less trunk movement in patients, due to stronger reflexes. We interpret these changes as reflecting protective behavior. Graphic abstract: These slides can be retrieved under Electronic Supplementary Material.[Figure not available: see fulltext.].

@en

This study aimed to assess modulation of lower leg muscle reflex excitability and co-contraction during unipedal balancing on compliant surfaces in young and older adults. Twenty healthy adults (ten aged 18–30 years and ten aged 65–80 years) were recruited. Soleus muscle H-reflexes were elicited by electrical stimulation of the tibial nerve, while participants stood unipedally on a robot-controlled balance platform, simulating different levels of surface compliance. In addition, electromyographic data (EMG) of soleus (SOL), tibialis anterior (TA), and peroneus longus (PL) and full-body 3D kinematic data were collected. The mean absolute center of mass velocity was determined as a measure of balance performance. Soleus H-reflex data were analyzed in terms of the amplitude related to the M wave and the background EMG activity 100 ms prior to the stimulation. The relative duration of co-contraction was calculated for soleus and tibialis anterior, as well as for peroneus longus and tibialis anterior. Center of mass velocity was significantly higher in older adults compared to young adults (p< 0.001) and increased with increasing surface compliance in both groups (p< 0.001). The soleus H-reflex gain decreased with surface compliance in young adults (p= 0.003) , while co-contraction increased (pSOL,TA=0.003andpPL,TA<0.001). Older adults did not show such modulations, but showed overall lower H-reflex gains (p< 0.001) and higher co-contraction than young adults (pSOL,TA<0.001andpPL,TA=0.002). These results suggest an overall shift in balance control from the spinal level to supraspinal levels in older adults, which also occurred in young adults when balancing at more compliant surfaces.

@en

The human head-neck system requires continuous muscular stabilization in the presence of gravity and trunk motion. This chapter presents experimental and modeling efforts, applying mechanical perturbations to seated subjects, evaluating trunk and head motion, to investigate postural stabilization.

A detailed multisegment neck model has been developed including vestibular/visual and muscular feedback loops and cocontraction. Dynamic validation is presented in the frequency domain in all six motion directions. The neck model captures primary motion responses and interaction terms such as head rotation in response to seat translation. Results show major contributions of vestibular/visual feedback stabilizing the head in space while muscular feedback stabilizes the head on the torso. In addition, muscular feedback is essential to stabilize the individual vertebral joints and prevent neck buckling. The contribution of cocontraction is estimated to be minor in the neck. Validation in impact conditions shows that postural control parameters estimated that fitting the model to small-amplitude experimental data can predict postural responses in high-amplitude loading conditions reasonably well.

This manuscript focuses on the neck but also includes experiments with combined stabilization of the complete spine, measuring trunk and head motion, with a perspective toward full spine and full-body modeling. Lumbar stabilization has been captured using a simplified model by assuming a virtual pivot around L4/L5. The model uniquely separates stabilizing contributions of intrinsic stiffness and damping (including muscle cocontraction) and muscle feedback (length, velocity, and acceleration). The model parameters allowed us to estimate the relative contributions of intrinsic and reflexive stabilization and showed intrinsic contributions, similar to or larger than reflexive contributions in lumbar stabilization with horizontal perturbations to the trunk or pelvis. Experiments with a rotating pelvis showed relevant contributions of vestibular and visual feedback, which are more effective to minimize head than trunk rotation.

A full-body human model with multisegment spine was previously validated for impact and vertical vibration. Integrating the new detailed neck model in the full-body human model will enable simulation of full-body vibration and impact scenarios with realistic compliant seat models. Further experiments and modeling efforts will aim to capture sensory integration of visual and vestibular motion perceptions in relation to posture maintenance and motion sickness.@en

Trunk stabilization is required to control posture and movement during daily activities. Various sensory modalities, such as muscle spindles, Golgi tendon organs and the vestibular system, might contribute to trunk stabilization and our aim was to assess the contribution of these modalities to trunk stabilization. In 35 healthy subjects, upper-body sway was evoked by continuous unpredictable, force-controlled perturbations to the trunk in the anterior direction. Subjects were instructed to either ‘maximally resist the perturbation’ or to ‘relax but remain upright’ with eyes closed. Frequency response functions (FRFs) of admittance, the amount of movement per unit of force applied, and reflexes, the modulation of trunk extensor activity per unit of trunk displacement, were obtained. To these FRFs, we fitted physiological models, to estimate intrinsic trunk stiffness and damping, as well as feedback gains and delays. The different model versions were compared to assess which feedback loops contribute to trunk stabilization. Intrinsic stiffness and damping and muscle spindle (short-delay) feedback alone were sufficient to accurately describe trunk stabilization, but only with unrealistically low reflex delays. Addition of muscle spindle acceleration feedback or inhibitory Golgi tendon organ feedback yielded realistic delays and improved the model fit, with a significantly better model fit with acceleration feedback. Addition of vestibular feedback did not improve the model fit. In conclusion, muscle spindle feedback and intrinsic mechanical properties are sufficient to describe trunk stabilization in the sagittal plane under small mechanical perturbations, provided that muscle spindles encode acceleration in addition to velocity and position information.@en

The goal of this study was to investigate the human ability to stabilize the trunk in space during pelvic tilt. Upper body sway was evoked in kneeling-seated healthy subjects by angular platform perturbations with a rotation around a virtual lowback pivot point between the L4 and L5 vertebrae. To investigate motor control modulation, variations in task instruction (balance naturally or minimize trunk sway), vision (eyes open or closed), and perturbation bandwidth (from 0.2 up to 1, 3, or 10 Hz) were applied. Cocontraction and proprioceptive muscle spindle feedback were associated with minimizing low-back flexion/extension (trunk-on-pelvis stabilization), while vestibular and visual feedback were supposed to contribute to trunk-in-space stabilization. Trunk-in-space stabilization was only observed with the minimize trunk sway task instruction, while the task instruction to balance naturally led to trunk-on-pelvis stabilization with trunk rotations even exceeding the perturbations. This indicates that vestibular feedback is used when minimizing trunk sway but has only a minor contribution during natural trunk stabilization in the sagittal plane. The eyes open condition resulted in reduced global trunk rotations and increased global trunk reflexive responses, demonstrating effective visual contributions to trunk-inspace stabilization. On the other hand, increasing perturbation bandwidth caused a decreased feedback contribution leading to deteriorated trunk-in-space stabilization.

@en