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In vivo kinetics with rapid perturbation experiments in Saccharomyces cerevisiae using a second-generation BioScope

Journal article (2006) - MR Mashego, W.M. van Gulik, JL Vinke, D Visser, J.J. Heijnen

In vivo kinetics of primary metabolism in Saccharomyces cerevisiae studied through prolonged chemostat cultication

Journal article (2006) - L Wu, MR Mashego, A. ten Pierick, JL Vinke, C. Ras, J.C. van Dam, WA van Winden, W.M. van Gulik, J.J. Heijnen

Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of C-13-labeled primary metabolites

Journal article (2005) - WA van Winden, J.C. van Dam, C. Ras, RJ Kleijn, JL Vinke, W.M. van Gulik, J.J. Heijnen

Changes in the metabolome of Saccharomyces cerevisiae associated with evolution in aerobic glucose-limited chemostats

Journal article (2005) - MR Mashego, MLA Jansen, JL Vinke, W.M. van Gulik, J.J. Heijnen

Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards

Journal article (2005) - L Wu, MR Mashego, J.C. van Dam, A. ten Pierick, JL Vinke, C. Ras, WA van Winden, W.M. van Gulik, J.J. Heijnen

An improved bioscope design: a system for continuous pulse experiments

Poster (2004) - MR Mashego, JR Corcoi, JL Vinke, W.M. van Gulik, J.J. Heijnen

Metabolome analysis by isotope dilution mass spectrometry using fully-labeled cell extracts as internal standards

Poster (2004) - L Wu, MR Mashego, J.C. van Dam, A. ten Pierick, JL Vinke, C. Ras, WA van Winden, W.M. van Gulik, J.J. Heijnen

Micracle: Mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites.

Journal article (2004) - MR Mashego, L Wu, J.C. van Dam, C. Ras, JL Vinke, WA van Winden, W.M. van Gulik, J.J. Heijnen

Accurate determination of benzoic acid diffusion kinetics in s. cerevisiae using the Bioscope

Abstract (2004) - MTAP Kresnowati, WA van Winden, W.M. van Gulik, A. ten Pierick, JL Vinke, J.J. Heijnen

An improved Bioscope design: a system for continuous pulse experiments

Poster (2004) - MR Mashego, JL Vinke, W.M. van Gulik, J.J. Heijnen

Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation

Journal article (2003) - WA van Winden, W.M. van Gulik, D Schipper, Peter J.T. Verheijen, P Krabben, JL Vinke, J.J. Heijnen

Critical evaluation of sampling techniques for residual glucose determination in carbon-limited chemostat culture of Saccharomyces cerevisiae

Journal article (2003) - MR Mashego, W.M. van Gulik, JL Vinke, J.J. Heijnen

Influence of temperature on growth and ajmalicine production by Catharantus roseus suspension cultures

Journal article (2002) - HJG ten Hoopen, JL Vinke, PRH Moreno, R Verpoorte, J.J. Heijnen

Energetics of growth and penicillin production in a high-producing strain of penicillium chrysogenum.

Journal article (2001) - W.M. van Gulik, MR Antoniewicz, WTAM de Laat, JL Vinke, J.J. Heijnen

Application of metabolic flux analysis for the identification of metabolic bottlenecks in the biosynthesis of penicillin-G.

Journal article (2000) - W.M. van Gulik, WTAM de Laat, JL Vinke, J.J. Heijnen

Abrasion of suspended biofilm pellets in airlift reactors: Importance of shape, structure and particle concentration.

Journal article (1997) - A Gjaltema, JL Vinke, Mark C.M. van Loosdrecht, J.J. Heijnen

JL Vinke

Authored