Theconstructionofgeneregulatorymodelsfrommicroarraytime-seriesdatahasreceivedmuchattention.Hereweproposeamethodthatextendsstandardcorrelationnetworkstoincorporateexplicittimeslices.Themethodisappliedtoatime-seriesdatasetofastudyongeneexpressioninthedevelopmentalphaseofzebra¿sh.Re
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Theconstructionofgeneregulatorymodelsfrommicroarraytime-seriesdatahasreceivedmuchattention.Hereweproposeamethodthatextendsstandardcorrelationnetworkstoincorporateexplicittimeslices.Themethodisappliedtoatime-seriesdatasetofastudyongeneexpressioninthedevelopmentalphaseofzebra¿sh.Resultsshowthatthemethodisabletodistinguishrealrelationsbetweengenesfromthedata.Theserelationsareexplicitlyplacedintime,allowingforabetterunderstandingofgeneregulation.ThemethodanddatanormalisationprocedurehavebeenimplementedusingtheRstatisticallanguageandareavailablefromhttp://zebrafish.liacs.nl/supplements.html.@en