Unraveling proteins at the single molecule level using nanopores

Doctoral thesis (2019)

Authors

L. Restrepo Perez BN/Chirlmin Joo Lab - AS

Contributors

C. Dekker (supervisor)
C. Joo BN/Chirlmin Joo Lab - AS (supervisor)
Research Group
BN/Chirlmin Joo Lab (AS) (TU Delft)
Copyright: © 2019 L. Restrepo Perez
DOI: https://doi.org/10.4233/uuid:a431659a-da38-42a5-be17-05b8c241e355
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Published Date

2019

Language

English

Reuse Rights

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Faculty

Applied Sciences

Department

BN/Bionanoscience

Research Group

BN/Chirlmin Joo Lab

Abstract

The function and phenotype of a cell is determined by a complex network of interactions between DNA, RNA, proteins and metabolites. Therefore, a comprehensive approach that integrates genomics, transcriptomics, proteomics, and metabolomics is necessary to achieve full understanding of biological processes and disease. Recent technological developments have mostly focused on the study of genomes. DNA sequencing has become fast, cheap, and ubiquitous. The study of other -omes, especially the proteome, remains expensive and time-consuming...

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