The transport sector is the Netherlands’ second highest emitting sector, with 19% of the total energy demand. Where other sectors are becoming more sustainable, the transport sector is one of the most difficult to decarbonise despite the many studies in this field. This research aims to gather a list of potential measures and combine them to reach an 80% reduction of emissions in 2040 for the hinterland freight corridor of Rotterdam - Venlo with a high rail freight intensity. A list of potential measures was established with literature studies and expert interviews. With a normative scenario design approach, an iterative process resulted in a list of 8 potential measures with a set of targets for these measures. After computation with the DeCaMod model a reduction of 80% is achieved on the corridor. The results showed that for this corridor, the reduction depends on the availability and adaptability of biodiesels and the electrification of vehicles and vessels. In contrast, measures aiming to improve logistics efficiency do reduce the total energy required but are less effective in reducing carbon dioxide emissions.