In recent years, the frequent occurrence of bus fire accidents has caused public concern in China, impacting the safe operation of urban transportation seriously. A cross-sectional survey was conducted to evaluate the safety & security (S&S) level of attitude and knowledge in relation to bus fires among residents in Fuzhou city, Fujian Province. 200 passengers from 6 bus terminals and 10 bus stations were selected as study subject. The results show that the S&S attitude and knowledge differ by gender, age, education background, occupation, and the frequency of taking a bus. The educational level significantly influences the S&S attitude and knowledge of the respondents, showing a positive correlation. Similarly, the passengers who take a bus frequently are more likely to display higher S&S attitude and knowledge scores. The participants working in governments and serving as managers in companies scored higher in attitude than the staff and students. A minority of respondents are concerned with bus fire S&S in their daily lives. Many passengers pay not much attention to the safety instructions when taking a bus. Some suggestions are given to improve S&S situation of bus transportation. The research results can lay the foundation for local governments, bus transport operators, and relevant safety organizations to establish a series of safety policies or regulations with respect to bus fires.