Natural gas accounts for just under a quarter of global energy demand. The gas is mainly delivered through pipelines, but is increasingly shipped overseas by liquefying it to LNG at -162 degrees Celcius. Fluids, containing free surfaces inside ships are likely to start sloshing, as ships move on waves. These fluids induce impact loading on the walls of the tanks. These impacts induce amplified motions in the tanks membranes in the order of millimeters to centimeters,resulting in permanent deformation that could exceed acceptable risk levels. In the industry one case of plastic deformation in the corrugated membranes of the LNG tanks was observed (Gavory and de Seze, 2009), but leakage was prevented. A growing desire for understanding sloshing behaviour raised and action was taken under the name of SLOHEL a JIP. Full scale experiments have been carried out. For investigating detailed structural response on the effect of Fluid-Structure Interaction on a prediction of the plastic deformation of a Mark III membrane, subjected to a local wave impact, a numerical application was carried out. In this thesis, the experiments became input for a numerical Fluid-Structure Interaction model, that is strong two-way coupled. The structural response of a local wave impact is analysed using LS Dyna. Two-way|coupled and one-way|uncoupled results are compared. The pressures of the fluid model have been validated after making simplifications and are within a range of ±10% compared to measured results of the SLOSHEL experiments for an wave impact velocity of 7 m/s. In the simulations three high pressure stages are identified on an impact between two corrugations. First, initial impact. Thereafter, lower corrugation impact ending with upper corrugation impact. At stage 3 large deformations were found in the foam layer behind the stainless steel membrane and for higher impact velocities also in the corrugated membrane. Uncoupled simulations, in which the structure is considered as rigid for the fluid solver, but is able to respond flexible in the structural solver, were performed. In coupled simulations, a full interactive model is considered in which pressures update as a result of structural displacements. This results in dry frequencies for uncoupled simulations and wet frequencies for coupled simulations. It was found that pressures in uncoupled simulations are in often higher. Displacements in the foam show for all cases higher displacements (10-25%) for uncoupled simulations. The plastic strains in the corrugated membrane are higher for high impact velocities (50-100%) for uncoupled simulations. The significance of accounting coupled Fluid-Structure Interaction increases when deformations become non-linear. For this specific case, when yield stress of the corrugations in the membrane is exceeded id est when plastic strain occurs, uncoupled simulations are not able to obtain accurate predictions in structural response.