We present the production of ^58mCo on a small, 13 MeV medical cyclotron utilizing a siphon style liquid target system. Different concentrated iron(III)-nitrate solutions of natural isotopic distribution were irradiated at varying initial pressures and subsequently separated by solid phase extraction chromatography. The radio cobalt (^58m/gCo and ⁵⁶Co) was successfully produced with saturation activities of (0.35 ± 0.03) MBq μA⁻¹ for ^58mCo with a separation recovery of (75 ± 2) % of cobalt after one separation step utilizing LN-resin.

Medical isotope production of ¹¹C is commonly performed in gaseous targets. The power deposition of the proton beam during the irradiation decreases the target density due to thermodynamic mixing and can cause an increase of penetration depth and divergence of the proton beam. In order to investigate the difference how the target-body length influences the operation conditions and the production yield, a 12 cm and a 22 cm Nb-target body containing N₂/O₂ gas were irradiated using a 13 MeV proton cyclotron. It was found that the density reduction has a large influence on the pressure rise during irradiation and the achievable radioactive yield. The saturation activity of [¹¹C]CO₂ for the long target (0.083 Ci/μA) is about 10% higher than in the short target geometry (0.075 Ci/μA).