The YEASTRACT (http://www.yeastract.com) information system is a tool for the analysis and prediction of transcription regulatory associations in Saccharomyces cerevisiae. Last updated in June 2013, this database contains over 200 000 regulatory associations between transcription factors (TFs) and target genes, including 326 DNA binding sites for 113 TFs. All regulatory associations stored in YEASTRACT were revisited and new information was added on the experimental conditions in which those associations take place and on whether the TF is acting on its target genes as activator or repressor. Based on this information, new queries were developed allowing the selection of specific environmental conditions, experimental evidence or positive/negative regulatory effect. This release further offers tools to rank the TFs controlling a gene or genome-wide response by their relative importance, based on (i) the percentage of target genes in the data set; (ii) the enrichment of the TF regulon in the data set when compared with the genome; or (iii) the score computed using the TFRank system, which selects and prioritizes the relevant TFs by walking through the yeast regulatory network. We expect that with the new data and services made available, the system will continue to be instrumental for yeast biologists and systems biology researchers.@en

This paper describes the Numerical and Physical Modelling components of the main project entitled "Viability study of the artificial surfing reef of S. Pedro do Estoril". These studies aim to establish the main characteristics (dimensions, orientation and location) of the artificial surfing reef for S. Pedro do Estoril and to analyze its hydrodynamic peifonnance for different incident wave conditions. The main conclusions of both studies were that the reef solution permits the improvement of the surf conditions in the area of S. Pedro do Estoril especially for the most frequent wave in the region. However, in both studies some problems related with strong reflection and vortices in the reef's corners where detected and should be improved in the final solution.@en