This paper presents a two-stage simheuristics-based framework for optimizing bridge maintenance scheduling strategies in a highway transportation network under uncertainty considering bridge life-cycle reliability and the effects of different maintenance interventions. The design variables of the optimal bridge maintenance scheduling problem are the preventive maintenance schedules for all bridges in the network, with the conflicting objectives of minimizing total maintenance cost and total travel time over the life cycle of bridges. The outcome of the first stage of the framework is a Pareto front of deterministic optimal solutions, which are then tested in the second stage to measure their performance under uncertainty.@en