In the face of escalating global emissions and rising awareness of the dangers of climate change, there is a need for sustainability initiatives across all industry sectors. Within the shipping industry, this is leading to a resurgence of interest in wind-assisted propulsion systems. This research investigates the hydrodynamic design of a wind-assisted cruise ship, aiming to redefine the image of the historically very polluting cruise industry by designing a vessel aimed at achieving 50% propulsive fuel savings through wind-assisted propulsion. The literature review provides the broad theoretical and computational background necessary for the design evaluation. The description of the historical evolution of wind propulsion, as well as state-of-the- art wind-assisted vessels and emerging concepts, provides the inspiration for the design investigation. A detailed hydrodynamic analysis was conducted, focusing on variations in hull design (B/T ratio, dead- rise angle) and appendage design (skegs, passive and active anti-drift fins). The efficacy of the mod- ifications was evaluated on an operational level using power prediction programs, allowing for perfor- mance assessments in varying conditions. A semi-empirical approach for the prediction of hydrodynamic forces and moments under drift using the maneuvering tool SURSIM is hypothesized as a computationally light alternative to numerical methods. However, SURSIM was found not to have the required fidelity to accurately predict the lift coefficient of the hull at small drift angles. Therefore, a computational fluid dynamics (CFD) approach was adopted for the determination of the hydrodynamic loads. The optimal unappended cruise ship design resulted in fuel savings of 34.5%. Optimal hydrodynamic efficiency favors a hull optimized for minimal resistance, and a retractable, active angle-of-attack fin for improved side force and yaw moment balance. The introduction of the fin led to an increase in fuel savings to 37.3%. Notable improvements in ship maneuverability can also be expected based on significantly reduced rudder actuation in sailing conditions. Operational variations have a large impact on fuel savings. Using the wind statistics of the N. Atlantic Holland America Line increased fuel savings to 48%, compared to the MEPC.1/Circ.896 standard. Con- siderable further gains can be achieved through the efficient handling of surplus wind power. Allowing a variable operational speed between 10.6kn and 20kn instead of a fixed speed of 12kn increased the fuel savings on the N. Atlantic route to 56.7%. Wind-assisted propulsion can be a viable strategy for significant fuel savings beyond 50%, and efficient appendage design can meaningfully improve the ship’s performance. Accurate prediction of fuel sav- ings requires clear knowledge of the operational conditions and control strategies. Further investigation of the detailed appendage design, and comparison of variable speed operation to the employment of a regenerative propeller mode is recommended. This thesis contributes to the evolving discourse on sustainable maritime transport, specifically within the cruise ship sector, by providing a comprehensive analysis of wind-assisted propulsion’s potential benefits.