MH

M. Hulsman

53 records found

Authored

We introduce a multi-scale kernel diffusion framework and apply it to a large collection of murine retroviral insertional mutagenesis data. The diffusion strength plays the role of scale parameter. As a result, in addition to detecting genes with frequent mutations in their genom ...

Scale-spaces from protein networks

How diffusion profiles reveal functional information in physical interaction topologies

Summary Understanding the living cell as a system of interconnected components is one of the key contemporary challenges. This is a complex problem, in which different types of functional interactions play a role, each operating across multiple distinct scales. How do functiona ...