The research of the thesis explores to what extent a multi-species design practice in architecture based on affordances informed by the act of human and non-human space-making in abandoned ruins helps to achieve a symbiotic relation between architecture and biodiversity. For this purpose, a theoretical framework triangulating affordances, multi-species design and architecture was developed. This was done throughout different exploratory methods such as reviewing literature, as well as an on-field studies of the abandoned ruin “Palácio Ford” in Porto, Portugal. The architectural project is about the design of a multi-species residency consisting of different kinds of towers that contribute to the growth of an urban forest by interaction with the environment. The interventions were developed as Baubotanik structures which combine living trees and technical construction methods in one object. Thus, the project explores new ways of living in a growing architecture which forms an urban forest within the city of Porto.