Advancing Deep Hyperthermia: the design and realisation of a Microwave Tomography and Hyperthermia treatment system

Master thesis (2024)

Authors

M.J.A. Jansen Mechanical Engineering

Contributors

Koen Dongen ImPhys/Medical Imaging - AS (mentor)
Massimiliano Zanoli Erasmus MC (mentor)
Nazlı Tümer Biomaterials & Tissue Biomechanics - Mechanical, Maritime and Materials Engineering (graduation committee member)
B. Rieger ImPhys/Computational Imaging - AS (graduation committee member)
Faculty
Mechanical Engineering, Mechanical Engineering
More Info
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Published Date

11-07-2024

Language

English

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Faculty

Mechanical Engineering

Abstract

This thesis is concerned with the technical, physical and computational challenges regarding
the incorporation of microwave tomography in hyperthermia treatments. Hyperthermia is a
clinical technique in which tumorous tissue is heated to gain therapeutic effect for concurrent
radiotherapy. Hyperthermia by microwaves, as performed at the Erasmus Medical Center,
suffers from uncertainties and lacking control. To relieve the burden of uncertainties regarding
dielectric properties and patient positioning, microwave tomography can be used in hyperthermia systems. This could also improve treatments, as it would offer more possibilities for
controlling the delivery. This work is focused on relieving several practical limitations to the
integration of tomography, rather than researching its possibilities. This thesis is accompanied by the literature research “Advancements in Microwave Tomography and Hyperthermia
Treatments” by the same author.