An Estimation Perspective on Breathing Effort Disturbances in Mechanical Ventilation

Journal article (2023)

Authors

Lars Van De Kamp Demcon Advanced Mechatronics, Eindhoven University of Technology
B. G B Hunnekens Demcon Advanced Mechatronics
Nathan van de Wouw University of Minnesota, Eindhoven University of Technology
T.A.E. Oomen Team Jan-Willem van Wingerden - Mechanical, Maritime and Materials Engineering , Eindhoven University of Technology
Research Group
Team Jan-Willem van Wingerden (Mechanical, Maritime and Materials Engineering) (TU Delft)
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Published Date

2023

Language

English

Faculty

Mechanical, Maritime and Materials Engineering

Department

Delft Center for Systems and Control

Research Group

Team Jan-Willem van Wingerden

Abstract

Estimation of relevant lung parameters and the breathing effort of a ventilated patient is essential to keep track of the patient's clinical condition. The aim of this paper is to investigate the major challenges of estimating the patient's condition with parametric models. The main method is a linear regression framework, where identifiability and persistence of excitation aspects are clearly unraveled. Different approaches for improving estimation accuracy are outlined. As an illustration, one of the solution strategies is implemented, which leads to accurate estimates of the breathing effort and relevant lung parameters.