Manipulation, Sampling and Inactivation of the SARS-CoV-2 Virus Using Nonuniform Electric Fields on Micro-Fabricated Platforms

A Review

Review (2023)

Authors

D. Mantri Student
L.F.A. Wymenga Electronic Components, Technology and Materials - EEMCS
J. van Turnhout Team Erik Offerman - Mechanical, Maritime and Materials Engineering
H.W. van Zeijl Electronic Components, Technology and Materials - EEMCS
Kouchi Zhang Electronic Components, Technology and Materials - EEMCS
Research Group
Team Erik Offerman (Mechanical, Maritime and Materials Engineering) (TU Delft)
Copyright: © 2023 D. Mantri, L.F.A. Wymenga, J. van Turnhout, H.W. van Zeijl, Kouchi Zhang
DOI: https://doi.org/10.3390/mi14020345
More Info
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Published Date

2023

Language

English

Faculty

Mechanical, Maritime and Materials Engineering

Department

Materials Science and Engineering

Research Group

Team Erik Offerman

Abstract

Micro-devices that use electric fields to trap, analyze and inactivate micro-organisms vary in concept, design and application. The application of electric fields to manipulate and inactivate bacteria and single-celled organisms has been described extensively in the literature. By contrast, the effect of such fields on viruses is not well understood. This review explores the possibility of using existing methods for manipulating and inactivating larger viruses and bacteria, for smaller viruses, such as SARS-CoV-2. It also provides an overview of the theoretical background. The findings may be used to implement new ideas and frame experimental parameters that optimize the manipulation, sampling and inactivation of SARS-CoV-2 electrically.