A miniaturized EHT platform for contractile tissue measurements

Poster (2019)

Authors

M. Dostanic Electronic Components, Technology and Materials - EEMCS
Laura Windt Leiden University Medical Center
Jeroen Stein Leiden University Medical Center
Berend J. van Meer Leiden University Medical Center
Massimo Mastrangeli Electronic Components, Technology and Materials - EEMCS
Christine Mummery Leiden University Medical Center
Pasqualina M Sarro Electronic Components, Technology and Materials - EEMCS
Research Group
Electronic Components, Technology and Materials (EEMCS) (TU Delft)
Copyright: © 2019 M. Dostanic, Laura Windt, Jeroen Stein, Berend van Meer, Massimo Mastrangeli, Christine Mummery, Pasqualina M Sarro
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Published Date

10-12-2019

Language

English

Reuse Rights

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Faculty

Electrical Engineering, Mathematics and Computer Science

Department

Microelectronics

Research Group

Electronic Components, Technology and Materials

Abstract

We presented the smallest and best characterised EHT devices to date. The devices were fabricated by wafer-scale silicon and polymer processing, characterised by nanoindentation and finite-element simulations, and transferred to 96-well plates for cell seeding and optical tracking of bundle contraction. Cell bundles remained functional for at least 18 days. Pacing electrodes and strain sensors will be added for improved bundle control.