Gravitational Wave detectors require feedback control to control the length between the sensitive components of the detector. The degrees of freedom in the control system are inherently coupled and the level of interaction furthermore varies over time. A systematic control design approach for the feedback controllers is presented which provides a guide on how to cope with the varying levels of interaction. A new controller for one of the loops has been designed and experimental results measured on the Gravitational Wave detector Advanced Virgo show a significant reduction in the root mean square error of the loop with the new controller.