Radio-loud quasars at high redshift (z ≥ 4) are rare objects in the universe and rarely observed with Very Long Baseline Interferometry (VLBI). But some of them have flux density sufficiently high for monitoring of their apparent position. The instability of the astrometric positions could be linked to the astrophysical process in the jetted active galactic nuclei in the early universe. Regular observations of the high-redshift quasars are used for estimating their apparent proper motion over several years. We have undertaken regular VLBI observations of several high-redshift quasars at 2.3 GHz (S band) and 8.4 GHz (X band) with a network of five radio telescopes: 40 m Yebes (Spain), 25 m Sheshan (China), and three 32 m telescopes of the Quasar VLBI Network (Russia)—Svetloe, Zelenchukskaya, and Badary. Additional facilities joined this network occasionally. The sources have also been observed in three sessions with the European VLBI Network in 2018-2019 and one Long Baseline Array experiment in 2018. In addition, several experiments conducted with the Very Long Baseline Array in 2017-2018 were used to improve the time sampling and the statistics. Based on these 37 astrometric VLBI experiments between 2017 and 2021, we estimated the apparent proper motions of four quasars: 0901+697, 1428+422, 1508+572, and 2101+600.

Very Long Baseline Interferometry (VLBI) offers unrivalled resolution in studies of celestial radio sources. The subjects of interest of the current IAU Symposium, the Active Galactic Nuclei (AGN) of all types, constitute the major observing sample of modern VLBI networks. At present, the largest in the world in terms of the number of telescopes and geographical coverage is the European VLBI Network (EVN), which operates under the "open sky"policy via peer-reviewed observing proposals. Recent EVN observations cover a broad range of science themes from high-sensitivity monitoring of structural changes in inner AGN areas to observations of tidal eruptions in AGN cores and investigation of redshift-dependent properties of parsec-scale radio structures of AGN. All the topics above should be considered as potentially rewarding scientific activities of the prospective African VLBI Network (AVN), a natural "scientific ally"of EVN. This contribution briefly describe the status and near-term strategy for the AVN development as a southern extension of the EVN-AVN alliance and as an eventual bridge to the Square Kilometre Array (SKA) with its mid-frequency core in South Africa.