Aviation is a large contributor to anthropogenic climate change through its emissions, particularly through nitrogen oxides (NOx), which reacts to Ozone in the atmosphere. Due to the emission of NOx, the ozone budget of the atmosphere is disturbed which results in an increase in the Earth’s surface temperature. To mitigate this effect, the variability of NOx and ozone due to aviation must be properly understood, which can be assessed through measurements in the atmosphere. NOx from aviation has been successfully measured in fresh plumes of aircraft, however, research has pointed out that the variability of ozone in the atmosphere is rather high, making it doubtful whether the perturbation due to aviation is detectable except under specific meteorological conditions such as high-pressure systems. This thesis assesses whether there is a correlation between high-pressure systems and the concentration of NOx from aviation and its produced ozone in those systems. With the result of this assessment recommendations are formulated which aid in designing future measurement campaigns of ozone from aviation.