This paper applies the distribution network reconfiguration problem to existing networks. The medium voltage distribution network of the Dutch DSO Alliander is operated using a radial topology. By optimizing this topology it is possible to reduce the energy losses caused by the cable impedances. Various solutions algorithms have been compared for this distribution network reconfiguration problem, while taking into account network capacity and voltage levels. A Genetic algorithm combined with a Greedy demeshing starting condition yields the best results. Applying the algorithm on real life distribution networks shows with 226 buses and 406 buses yield a reduction in power losses of 15% and 27% respectively.@en