Seaports are critical to the global supply chain, and as maritime trade grows with globalization, inefficiencies in port call processes and ship waiting times are increasing. This research develops a framework for Port Call Optimization (PCO) models to support collaboration and decision-making between stakeholders within the Nautical Chain (NC) and terminals. The Design Science Research (DSR) approach provides a systematic way to design a PCO tool for a port that is backed by a strong knowledge base. Integrating this approach with the co-design process involving user input ensures that the tool aligns with client needs and trends. This study uncovers a framework to assess the prerequisites for PCO tool implementation and develops steps to build a roadmap for PCO tools that incorporate the intricacies of different port governance structures. The findings from this research lays the groundwork for future research regarding the implementation of a PCO tool by bridging the gap between the fragmented research in this domain.