Telemedicine has the potential to significantly improve healthcare delivery in low-resource settings (LRS), yet its adoption remains low despite its benefits. This study explores the organizational factors of telemedicine adoption in LRS using qualitative research methods and adapting the Unified Theory of Acceptance and Use of Technology (UTAUT) framework. The research identifies key barriers and facilitators, and a modified framework is proposed to better address the adoption dynamics. The study provides valuable insights into how telemedicine adoption can be examined among healthcare professionals in LRS, highlighting the need for further validation of the proposed framework.