The main goal of the TerraSAR-X Add-On for Digital Elevation Measurements (TanDEM-X) mission is the generation of a global digital elevation model (DEM) of unprecedented accuracy and coverage. The global TanDEM-X DEM product became available in 2016, surpassed all expectations, and became a reference for a wide range of Earth science, commercial, and geospatial applications. In addition, new information products, such as DEM change maps (DCMs), have been developed and are available to the geoscience and remote sensing community. Beyond the operational products, new science applications have been demonstrated and are summarized in this article, along with experimental data acquisitions. This article also aims to provide an overview of science activities with TanDEM-X data and science data acquisitions planned for the coming years.