This paper presents an optimization framework for highway infrastructure elements that integrates risk profiles (for infrastructures) and economic aspects. One main goal is to assess the necessary additional effort to satisfy performance constraints under different scenarios of climate change. In order to be easily deployable by national road administrations (NRAs), this framework is built in such a way that it can be embedded into asset management systems that include an inventory of the asset, inspection strategies (to report element conditions and safety defects) and decision-making for funds allocation. Using the inventory of the asset and condition assessment as input, the method aims to determine some degradation profiles for bridge components, retaining walls and steep embankments. The method to determine the degradation process is detailed so that any infrastructure manager can determine their own deterioration processes based on the inventory and condition assessment of their stock. Combining degradation of highway infrastructures with a risk analysis, this paper presents an optimization framework to determine optimal management strategies.