C. Linne
2 records found
1
Authored
To bind or not to bind
DNA mediated multivalent interactions lead to superselectivity
To bind two entities together, an attractive interaction is needed. In biological systems, such interactions are often between ligands and receptors. But this interaction constantly breaks and forms because it is (too) weak. To ensure a lasting bond, the system can form multiple
...
Reliably distinguishing between cells based on minute differences in receptor density is crucial for cell-cell or virus-cell recognition, the initiation of signal transduction, and selective targeting in directed drug delivery. Such sharp differentiation between different surf ...