A joint academia-industry project, the Pile Soil Analysis (PISA) project, resulted in an empirical method for assessing the monotonic lateral loading response of large diameter monopiles. The method predicts four soil reactions, namely the distributed load and the distributed moment along the pile shaft, the pile base shear and the pile base moment. The method considers pile load test data and 3D numerical modelling. A 1D framework allows prediction of the four soil reactions. In this paper, a CPT-based approach is proposed to derive the four soil reaction components for use in a 1D model for conceptual design of monopiles in sand subject to monotonic lateral loading. The approach relies on results from 3D finite element analyses that were performed considering soil conditions for a sand site used in the PISA project (Dunkirk site). The results are compared to pile load test data from the PISA project, showing good agreement, particularly for load levels related to the serviceability limit state.