Bitumen, a crucial constituent in the composition of asphalt pavements, plays a vital role in the performance and durability of pavements. Bitumen undergoes aging over time due to complex interactions between its chemical components and various environmental factors. In this investigation, the study focuses on examining the aging process of bitumen under the combined influence of moisture and reactive oxygen species (ROS). The findings highlight the importance of considering ROS and moisture as critical factors contributing to accelerated aging. Results obtained from Fourier-transform infrared (FTIR) spectroscopy, SARA fractionation, and optical inverse microscope (OIM), as well as dynamic shear rheometer (DSR) examination, indicate that the concurrent influence of these factors induces significant aging in bitumen, with the extent of this impact being modulated by the bitumen's inherent aging susceptibility. The insights obtained from this study enhance strategies to justify the destructive impacts of aging, extending the operational lifespan of asphalt pavements.@en