Both 2D and 3D re-entrant designs are among the well-known prevalent auxetic structures exhibiting negative Poisson's ratio. The present study introduces novel analytical relationships for 2D re-entrant hexagonal honeycombs for both negative and positive ranges of the cell interior angle θ (θ<0 showing a negative Poisson's ratio). The derived analytical solutions are validated against finite element method (FEM) and experimental results. The results show that, compared to the analytical solutions available in the literature, the analytical relationships presented in this study provide the most accurate results for elastic modulus, Poisson's ratio, and yield stress. The analytical/computational tools are then implemented for designing Kinesio taping (KT) structures applicable to treatment of Achilles tendon injuries. One of the main features of the Achilles tendon is a natural auxetic behavior. Poisson's ratio distribution of an Achilles tendon is obtained using longitudinal and transverse strains and are then used to design and 3D print thermoplastic polyurethane (TPU) KT structures with non-uniform distribution of auxetic unit cells. The presented novel KT shows that it is capable of replicating the deformation and global and local Poisson's ratio distributions, similar to those of the Achilles tendon. Due to the absence of similar formulations and procedures in the literature, the results are expected to be instrumental for designing and 3D printing of flexible implants with unusual auxeticity.