The high level of realism of spiking neuron networks and their complexity require a substantial computational resources limiting the size of the realized networks. Consequently, the main challenge in building complex and biologically-accurate spiking neuron network is largely set by the high computational and data transfer demands. In this paper, we implement several efficient models of the spiking neurons with characteristics such as axon conduction delays and spike timing-dependent plasticity. Experimental results indicate that the proposed real-time data-flow learning network architecture allows the capacity of over 2800 (depending on the model complexity) biophysically accurate neurons in a single FPGA device.@en