Selective Peroxygenase-Catalysed Oxidation of Phenols to Hydroquinones

Journal article (2024)

Authors

Hugo Brasselet BT/Biocatalysis - AS
Fabian Schmitz Universität Düsseldorf
Katja Koschorreck Universität Düsseldorf
Vlada B. Urlacher Universität Düsseldorf
F. Hollmann BT/Biocatalysis - AS
T. Hilberath BT/Biocatalysis - AS
Research Group
BT/Biocatalysis (AS) (TU Delft)
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Published Date

2024

Language

English

Faculty

Applied Sciences

Department

BT/Biotechnologie

Research Group

BT/Biocatalysis

Abstract

An enzymatic method for the selective hydroxylation of phenols using a peroxygenase from Aspergillus brasiliensis (AbrUPO) is reported. A broad range of phenolic starting materials can be selectively transformed into the corresponding hydroquinones. Semi-preparative syntheses of several hydroquinones were realised without further optimization pointing out the applicability of this enzyme as biocatalyst.