Adsorption of molybdenum on Zr-based MOFs for potential application in the 99Mo/99mTc generator

Journal article (2021)

Authors

C. Ma RST/Applied Radiation & Isotopes - AS
A. Vasileiadis RST/Storage of Electrochemical Energy - AS
H.T. Wolterbeek RST/Applied Radiation & Isotopes - AS
A.G. Denkova RST/Applied Radiation & Isotopes - AS
P. Serra Crespo RST/Applied Radiation & Isotopes - AS
Research Group
RST/Applied Radiation & Isotopes (AS) (TU Delft)
Copyright: © 2021 C. Ma, A. Vasileiadis, H.T. Wolterbeek, A.G. Denkova, P. Serra Crespo
DOI: https://doi.org/10.1016/j.apsusc.2021.151340
More Info
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Published Date

2021

Language

English

Faculty

Applied Sciences

Department

RST/Radiation, Science and Technology

Research Group

RST/Applied Radiation & Isotopes

Abstract

The potential of the metal–organic framework UiO-66 and its functionalized derivatives for their utilization in the 99Mo/99mTc generator was assessed. Molybdenum adsorption experiments, structure characterization, molecular simulations and column experiments with molybdenum-99 were carried out. The results showed that the maximum molybdenum adsorption capacity achieved for UiO-66 was 335 mg g−1. Adsorption on the surface of the UiO-66 occurs via electrostatic interaction and DFT calculations verified the enhanced affinity between the adsorbents and the molybdenum ions by Zr-O-Mo coordination, anion-π as well as hydrogen bonds. In addition, the performance of a 99Mo/99mTc generator fabricated with Form-UiO-66 was evaluated. The results showed that adsorption was comparable with the experiments using non-active molybdenum and that the 99mTc elution efficiency of around 70% could be achieved without zirconium breakthrough.