Functional Convergence of Autonomic and Sensorimotor Processing in the Lateral Cerebellum

Romano, Vincenzo; Reddington, Aoibhinn L.; Cazzanelli, Silvia; Mazza, Roberta; Ma, Yang; Strydis, C.; Negrello, Mario; Bosman, Laurens W.J.; De Zeeuw, Chris Innocentius

Functional Convergence of Autonomic and Sensorimotor Processing in the Lateral Cerebellum

Journal article (2020)

Authors

Vincenzo Romano Erasmus MC

Aoibhinn L. Reddington Erasmus MC

Silvia Cazzanelli Erasmus MC

Roberta Mazza Erasmus MC

Yang Ma Erasmus MC

C. Strydis Erasmus MC

Mario Negrello Erasmus MC

Laurens W.J. Bosman Erasmus MC

Chris Innocentius De Zeeuw Erasmus MC, Netherlands Institute for Neuroscience

Affiliation

External organisation

Plasticity Electrophysiology Optogenetics Respiration Purkinje cells Cerebellum Phase dependent responses Sensorimotor behavior Whisker stimulation Whisking

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Published Date

07-07-2020

Language

English

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External organisation

Abstract

Romano et al. show that cerebellar Purkinje cell activity follows the respiratory rhythm during rest. Triggered by sensory input, Purkinje cells can alter their activity and thereby accelerate the timing of the next inspiration. Concomitantly, they also augment whisker movements, highlighting a coordinating role in aligning autonomic and sensorimotor behaviors.