Advanced MR Techniques for Preoperative Glioma Characterization

Part 2

Review (2023)

Authors

Gilbert Hangel Christian Doppler Laboratory for Precision Engineering for Automated In-Line Metrology, Medical University of Vienna
Bárbara Schmitz-Abecassis Medical Delta, Leiden University Medical Center
Joana Pinto University of Oxford
Nico Sollmann Technische Universität München, University Hospital Ulm
C. Tseng ImPhys/Vos group - AS , ImPhys/Computational Imaging - AS , Medical Delta
F.M. Vos ImPhys/Computational Imaging - AS , ImPhys/Vos group - AS , Medical Delta , Erasmus MC
E.A.H. Warnert Erasmus MC
M. Smits Medical Delta , Erasmus MC
Jan Petr Institute of Radiation Physics
More Authors... External organisation
Research Group
ImPhys/Computational Imaging (AS) (TU Delft)
Copyright: © 2023 Gilbert Hangel, Bárbara Schmitz-Abecassis, Joana Pinto, Nico Sollmann, C. Tseng, F.M. Vos, E.A.H. Warnert, M. Smits, Jan Petr, More Authors
DOI: https://doi.org/10.1002/jmri.28663
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Published Date

2023

Language

English

Faculty

Applied Sciences

Department

ImPhys/Imaging Physics

Research Group

ImPhys/Computational Imaging

Abstract

Preoperative clinical MRI protocols for gliomas, brain tumors with dismal outcomes due to their infiltrative properties, still rely on conventional structural MRI, which does not deliver information on tumor genotype and is limited in the delineation of diffuse gliomas. The GliMR COST action wants to raise awareness about the state of the art of advanced MRI techniques in gliomas and their possible clinical translation. This review describes current methods, limits, and applications of advanced MRI for the preoperative assessment of glioma, summarizing the level of clinical validation of different techniques. In this second part, we review magnetic resonance spectroscopy (MRS), chemical exchange saturation transfer (CEST), susceptibility-weighted imaging (SWI), MRI-PET, MR elastography (MRE), and MR-based radiomics applications. The first part of this review addresses dynamic susceptibility contrast (DSC) and dynamic contrast-enhanced (DCE) MRI, arterial spin labeling (ASL), diffusion-weighted MRI, vessel imaging, and magnetic resonance fingerprinting (MRF). Evidence Level: 3. Technical Efficacy: Stage 2.