Amino Acid Profiling from Fingerprints Using Amide Stationary-Phase UPLC-MS

Book chapter (2019)

Authors

Ward Van Helmond Hogeschool van Amsterdam, Nederlands Forensisch Instituut (NFI)
M. de Puit OLD ChemE/Organic Materials and Interfaces, Nederlands Forensisch Instituut (NFI)
Research Group
OLD ChemE/Organic Materials and Interfaces
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Published Date

2019

Language

English

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Research Group

OLD ChemE/Organic Materials and Interfaces

Abstract

UPLC-MS is a commonly used technique to first separate complex samples and subsequently quantify molecules of interest. Herein we describe the use of UPLC-MS using an amide stationary phase to quantify non-derivatized amino acids extracted from fingerprints. As detector either a triple-quadrupole MS/MS or a TOF-MS detector was used. This method allows for a simple and fast sample preparation, which facilitates the analysis of large amounts of samples.

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