Biocatalysis engineering: the big picture

Journal article (2017)

Authors

R.A. Sheldon BT/Biocatalysis - AS , University of Witwatersrand
Roger A. Sheldon BT/Biocatalysis - AS , University of Witwatersrand
P.A. Cherando Pereira RID/Kernenergiewet Organisatie
Research Group
BT/Biocatalysis (AS) (TU Delft)
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Published Date

13-03-2017

Language

English

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Faculty

Applied Sciences

Department

BT/Biotechnologie

Research Group

BT/Biocatalysis

Abstract

In this tutorial review we describe a holistic approach to the invention, development and optimisation of biotransformations utilising isolated enzymes. Increasing attention to applied biocatalysis is motivated by its numerous economic and environmental benefits. Biocatalysis engineering concerns the development of enzymatic systems as a whole, which entails engineering its different components: substrate engineering, medium engineering, protein (enzyme) engineering, biocatalyst (formulation) engineering, biocatalytic cascade engineering and reactor engineering.

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