POLAR MAPPER

A computational tool for integrated visualization of protein interaction networks and mRNA expression data

Journal article (2009)

Authors

Joana Gonçalves Lisbon Technical University, Biocant, INESC-ID
Mário Grãos Biocant
Andre X. C. N. Valente Biocant, Universidade de Coimbra
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Published Date

06-10-2009

Language

English

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Abstract

Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.