Shape Morphing and Slice Shift Correction in Congenital Heart Defect Model Generation

Conference paper (2023)

Authors

Ashley Stroh Dassault Systèmes Simulia Corporation
Wim A. Helbing Erasmus MC
M. Peirlinck Medical Instruments & Bio-Inspired Technology - Mechanical, Maritime and Materials Engineering
Research Group
Medical Instruments & Bio-Inspired Technology (Mechanical, Maritime and Materials Engineering) (TU Delft)
Copyright: © 2023 Puck Pentenga, Ashley Stroh, Wouter van Genuchten, Wim A. Helbing, M. Peirlinck
DOI: https://doi.org/10.1007/978-3-031-35302-4_36
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Published Date

2023

Language

English

Reuse Rights

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Faculty

Mechanical, Maritime and Materials Engineering

Department

Biomechanical Engineering

Research Group

Medical Instruments & Bio-Inspired Technology

Abstract

Computational heart modeling is a promising approach for improving the prognosis of patients born with congenital heart defects. To create accurate physics-based digital cardiac twins of this population, it is crucial to accurately represent the highly diverse and unique subject-specific heart geometry. In young pediatric patients, this is a challenging endeavor given the lack of high-spatial-resolution imaging data and the risk of slice misalignment. In this study, we set up a multistep shape morphing and slice correction approach to accommodate these challenges and establish a population of biventricular heart models for a variety of healthy, Fallot, and Fontan pediatric patients.

Files

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- Embargo expired in 25-12-2023
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