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Kortenbout, A.J. (author), Costerus, Sophie (author), Dudink, Jeroen (author), de Jong, N. (author), de Graaff, Jurgen C. (author), Vos, H.J. (author), Bosch, Johan G. (author)Objective: Post-operative brain injury in neonates may result from disturbed cerebral perfusion, but accurate peri-operative monitoring is lacking. High-frame-rate (HFR) cerebral ultrasound could visualize and quantify flow in all detectable vessels using spectral Doppler; however, automated quantification in small vessels is challenging...journal article 2024
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Simoes dos Santos, D. (author), Baldini, L.B. (author), Vos, H.J. (author), Verweij, M.D. (author), de Jong, N. (author), van Neer, P.L.M.J. (author)The accurate determination of the transfer function of ultrasound transducers is important for their design and operational performance. However, conventional methods for quantifying the transfer function, such as hydrophone measurements, radiation force balance, and pulse-echo measurements, are costly and complex due to specialized equipment...journal article 2024
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Hopf, Y.M. (author), Simoes dos Santos, D. (author), Ossenkoppele, Boudewine W. (author), Noothout, E.C. (author), Chang, Z.Y. (author), Chen, Chao (author), Vos, H.J. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)This article presents an application-specific integrated circuit (ASIC) for catheter-based 3-D ultrasound imaging probes. The pitch-matched design implements a comprehensive architecture with high-voltage (HV) transmitters, analog front ends, hybrid beamforming analog-To-digital converters (ADCs), and data transmission to the imaging system....journal article 2024
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Gil Jimenez, A. (author), van Dijk, Nick (author), Vos, Joris L. (author), Lubeck, Yoni (author), van Montfoort, Maurits L. (author), Peters, Dennis (author), Hooijberg, Erik (author), Broeks, Annegien (author), Wessels, L.F.A. (author)Immune checkpoint inhibitors (ICI) can achieve remarkable responses in urothelial cancer (UC), which may depend on tumor microenvironment (TME) characteristics. However, the relationship between the TME, usually characterized by immune cell density, and response to ICI is unclear. Here, we quantify the TME immune cell densities and spatial...journal article 2024
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Battaglia, Thomas W. (author), Mimpen, Iris L. (author), Traets, Joleen J.H. (author), van Hoeck, Arne (author), Zeverijn, Laurien J. (author), Geurts, Birgit S. (author), de Wit, Gijs F. (author), Vos, Joris L. (author), Wessels, L.F.A. (author)Microbial communities are resident to multiple niches of the human body and are important modulators of the host immune system and responses to anticancer therapies. Recent studies have shown that complex microbial communities are present within primary tumors. To investigate the presence and relevance of the microbiome in metastases, we...journal article 2024
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Vos, Hidde (author), Lombardi, F. (author), Joshi, R. (author), Schmehl, R. (author), Pfenninger, Stefan (author)Novel wind technologies, in particular airborne wind energy (AWE) and floating offshore wind turbines, have the potential to unlock untapped wind resources and contribute to power system stability in unique ways. So far, the techno-economic potential of both technologies has only been investigated at a small scale, whereas the most significant...journal article 2024
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Proesmans, P. (author), Vos, Roelof (author)This paper focuses on the conceptual design optimization of liquid hydrogen aircraft and their performance in terms of climate impact, cash operating cost, and energy consumption. An automated, multidisciplinary design framework for kerosene-powered aircraft is extended to design liquid hydrogen-powered aircraft at a conceptual level. A...journal article 2024
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Simoes dos Santos, D. (author), Ossenkoppele, B.W. (author), Hopf, Y.M. (author), Soozande, Mehdi (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, Johan G. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), de Jong, N. (author)Objective: Described here is the development of an ultrasound matrix transducer prototype for high-frame-rate 3-D intra-cardiac echocardiography. Methods: The matrix array consists of 16 × 18 lead zirconate titanate elements with a pitch of 160 µm × 160 µm built on top of an application-specific integrated circuit that generates transmission...journal article 2024
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Murillo, Andrés (author), Taormina, R. (author), Tippenhauer, Nils Ole (author), Salaorni, Davide (author), van Dijk, Robert (author), Jonker, Luc (author), Vos, Simcha (author), Weyns, Maarten (author), Galelli, Stefano (author)Numerical simulation models are a fundamental tool for planning and managing smart water networks—an evolution of water distribution systems in which physical assets are monitored and controlled by information and communication technologies. While simulation models allow us to understand the interactions between physical processes and abstract...journal article 2023
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Kuschnerus, M. (author), Lindenbergh, R.C. (author), Vos, S.E. (author), Hanssen, R.F. (author)In the view of climate change, understanding and managing effects on coastal areas and adjacent cities is essential. Permanent Laser Scanning (PLS) is a successful technique to not only observe notably sandy coasts incidentally or once every year, but (nearly) continuously over extended periods of time. The collected point cloud observations...journal article 2023
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de Winter, J.C.F. (author), Koelmans, T.A. (author), Kokshoorn, M.H.J.L. (author), van der Valk, K.P. (author), Vos, Willem (author), Dodou, D. (author), Eisma, Y.B. (author)Chunking theory and previous eye-tracking studies suggest that expert chess players use peripheral vision to judge chess positions and determine the best moves to play. However, the role of peripheral vision in chess has largely been inferred rather than tested through controlled experimentation. In this study, we used a gaze-contingent paradigm...journal article 2023
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Guo, P. (author), Fool, F. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, Johan G. (author), de Jong, N. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author)This article presents a low-power and small-area transceiver application-specific integrated circuit (ASIC) for 3-D trans-fontanelle ultrasonography. A novel micro-beamforming receiver architecture that employs current-mode summation and boxcar integration is used to realize delay-and-sum on an N -element sub-array using N× fewer capacitive...journal article 2023
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Keshani, M. (author), Vos, Simcha (author), Proksch, S. (author)Software reuse is a common practice in modern software engineering to save time and energy while accelerating software delivery. Dependency managers like MAVEN offer a large ecosystem of reusable libraries that build the backbone of software reuse. Breaking changes, i.e., when an update to a library introduces incompatible changes that break...journal article 2023
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van Kouwen, Niels C. (author), Ton, A.M. (author), Vos, S.E. (author), Vijverberg, Thomas (author), Reniers, A.J.H.M. (author), Aarninkhof, S.G.J. (author)Many sand spits are morphodynamically complex landforms, that are either analysed with complex and expensive computational models or at a conceptual level. Therefore, most case studies on spits in different environments are descriptive. A novel method based on the use of polar coordinates was devised to quantitatively analyse spit...journal article 2023
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Wei, Luxi (author), Wahyulaksana, G. (author), Boni, Enrico (author), Noothout, E.C. (author), Duncker, Dirk J. (author), Tortoli, Piero (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Vos, H.J. (author)Objective: The aim of this study was to assess the feasibility and imaging options of contrast-enhanced volumetric ultrasound kidney vasculature imaging in a porcine model using a prototype sparse spiral array. Methods: Transcutaneous freehand in vivo imaging of two healthy porcine kidneys was performed according to three protocols with...journal article 2023
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Vos, K. (author), Splinter, K. D. (author), Palomar-Vázquez, J. (author), Pardo-Pascual, J. E. (author), Almonacid-Caballer, J. (author), Cabezas-Rabadán, C. (author), Kras, E. C. (author), Luijendijk, Arjen (author), Calkoen, F.R. (author)Satellite remote sensing is becoming a widely used monitoring technique in coastal sciences. Yet, no benchmarking studies exist that compare the performance of popular satellite-derived shoreline mapping algorithms against standardized sets of inputs and validation data. Here we present a new benchmarking framework to evaluate the accuracy of...journal article 2023
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Tseng, C. (author), Jaspers, Jaap (author), Romero, Alejandra Mendez (author), Wielopolski, Piotr (author), Smits, M. (author), van Osch, Matthias J.P. (author), Vos, F.M. (author)The arterial input function (AIF) plays a crucial role in estimating quantitative perfusion properties from dynamic susceptibility contrast (DSC) MRI. An important issue, however, is that measuring the AIF in absolute contrast-agent concentrations is challenging, due to uncertainty in relation to the measured (Formula presented.) -weighted...journal article 2023
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Caenen, Annette (author), Keijzer, Lana (author), Bézy, Stéphanie (author), Duchenne, Jürgen (author), Orlowska, Marta (author), van der Steen, A.F.W. (author), de Jong, N. (author), Bosch, Johan G. (author), Voigt, Jens Uwe (author), D’hooge, Jan (author), Vos, H.J. (author)Ultrasound-based shear wave elastography is a promising technique to non-invasively assess the dynamic stiffness variations of the heart. The technique is based on tracking the propagation of acoustically induced shear waves in the myocardium of which the propagation speed is linked to tissue stiffness. This measurement is repeated multiple...journal article 2023
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Nagtegaal, M.A. (author), Hermann, I. (author), Weingärtner, S.D. (author), Martinez-Heras, Eloy (author), Solana, Elisabeth (author), Llufriu, Sara (author), Gass, Achim (author), Poot, Dirk H.J. (author), van Osch, Matthias J.P. (author), Vos, F.M. (author), de Bresser, Jeroen (author)T<sub>2</sub>-hyperintense lesions are the key imaging marker of multiple sclerosis (MS). Previous studies have shown that the white matter surrounding such lesions is often also affected by MS. Our aim was to develop a new method to visualize and quantify the extent of white matter tissue changes in MS based on relaxometry properties. We...journal article 2023
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Vos, J. (author), de Winter, J.C.F. (author), Farah, H. (author), Hagenzieker, Marjan (author)Although much research is done on speed and gaze behaviour inside curves, there is little understanding of which cues drivers use to anticipate and slow down while approaching curves. Therefore, an on road experiment was conducted in which 31 participants drove through six freeway curves in their own car. During the experiment, look-ahead...journal article 2023