document

Spectral CT Thermometry for Thermal Liver Ablation: Applicability and Needle Artifact Reduction

Koetzier, Lennart (author)

Motivation: Effective management of liver tumors through thermal ablation requires precise monitoring of the ablation zone to ensure successful treatment outcomes. Computed tomography (CT) thermometry offers a promising non-invasive solution to monitor if tumor cells have been heated to the lethal temperature threshold. However, achieving...

master thesis 2024

document

Coherent Anti-Stokes Raman Spectroscopy (CARS)

Mazza, F. (author), Castellanos, Leonardo (author), Klyukin, Dmitry (author), Bohlin, G.A. (author)

Coherent anti-Stokes Raman scattering (CARS) spectroscopy has been used to provide gas-phase quantitative scalar information (e.g. temperature, density, and species concentrations) for more than 5 decades. This technique is renowned for its ability to realize non-intrusive in-situ measurements in harsh environments with excellent spatial and...

book chapter 2024

document

Ultrabroadband coherent Raman spectroscopy for reacting flows

Mazza, F. (author)

The present dissertation covers the development of ultrabroadband femtosecond/picosecond coherent Raman spectroscopy (CRS) to measure temperature and species concentrations in gas-phase chemically reacting flows.<br/>Since its first demonstration in 1965, CRS has been vastly employed as a non-linear optical spectroscopic technique to quantify...

doctoral thesis 2023

document

Multi-echo gradient echo pulse sequences: which is best for PRFS MR thermometry guided hyperthermia?

Feddersen, Theresa V. (author), Poot, Dirk H.J. (author), Paulides, Margarethus M. (author), Salim, Ghassan (author), van Rhoon, G.C. (author), Hernandez-Tamames, J.A. (author)

Purpose: MR thermometry (MRT) enables noninvasive temperature monitoring during hyperthermia treatments. MRT is already clinically applied for hyperthermia treatments in the abdomen and extremities, and devices for the head are under development. In order to optimally exploit MRT in all anatomical regions, the best sequence setup and post...

journal article 2023

document

POD–Kalman filtering for improving noninvasive 3D temperature monitoring in MR-guided hyperthermia

VilasBoas-Ribeiro, Iva (author), Nouwens, Sven A.N. (author), Curto, Sergio (author), Jager, Bram de (author), Franckena, Martine (author), van Rhoon, G.C. (author), Heemels, W. P.M.H. (author), Paulides, Margarethus M. (author)

Background: During resonance frequency (RF) hyperthermia treatment, the temperature of the tumor tissue is elevated to the range of 39–44°C. Accurate temperature monitoring is essential to guide treatments and ensure precise heat delivery and treatment quality. Magnetic resonance (MR) thermometry is currently the only clinical method to...

journal article 2022

document

High-temperature rotational-vibrational O_2^[sbnd]CO₂ coherent Raman spectroscopy with ultrabroadband femtosecond laser excitation generated in-situ

Mazza, F. (author), Griffioen, N. (author), Castellanos, Leonardo (author), Klyukin, Dmitry (author), Bohlin, G.A. (author)

We present ultrabroadband two-beam femtosecond/picosecond coherent Raman spectroscopy on the ro-vibrational spectra of CO₂ and O₂, applied for multispecies thermometry and relative concentration measurements in a standard laminar premixed hydrocarbon flame. The experimental system employs fs-laser-induced filamentation...

journal article 2022

document

Avoiding Pitfalls in Thermal Dose Effect Relationship Studies: A Review and Guide Forward

Carrapiço-Seabra, Carolina (author), Curto, Sergio (author), Franckena, Martine (author), van Rhoon, G.C. (author)

The challenge to explain the diffuse and unconclusive message reported by hyperthermia studies investigating the thermal dose parameter is still to be unravelled. In the present review, we investigated a wide range of technical and clinical parameters characterising hyperthermia treatment to better understand and improve the probability of...

review 2022

document

Water vapor in hydrogen flames measured by time-resolved collisional dephasing of the pure-rotational N₂ CARS signal

Castellanos, Leonardo (author), Mazza, F. (author), Bohlin, G.A. (author)

We present a novel diagnostic technique to probe water vapor (H₂O) concentration in hydrogen (H₂) combustion environments via the time-resolved measurement of the collisional dephasing of the pure-rotational coherent anti-Stokes Raman scattering (CARS) signal of nitrogen (N₂). The rotational Raman coherence of...

journal article 2022

document

Enhanced single – shot flame thermometry with femtosecond / picosecond CARS using a phase – characterized picosecond probe

Vijayaraghavan, Anand (author)

Hybrid fs/ps coherent anti-Stokes Raman CARS is a powerful laser diagnostic technique for thermometry and concentration measurements in chemically-reacting flows. The use of SHBC to generate the ps probe pulse is simple, robust, and relatively efficient. However, the presence of spectral sidebands in this pulse determines an additional...

master thesis 2021

document

Creating an antenna band for the myTemp system

Meijnders, Nathalie (author)

This graduation report describes the design process of the antenna band of the myTemp system. The myTemp system is a high accuracy core temperature measuring device, that uses an indigestible measuring pill and an antenna band to measure the temperature inside the intestines. It is mainly used in thermo-physiological or exercise-related research...

master thesis 2021

document

Development of CO2-O2 CARS thermometry and concentration measurements for applied flame diagnostics

Griffioen, Nathan (author)

In this M.Sc. thesis project a model is developed and validated that simulates the coherent anti-Stokes Raman scattering (CARS) signal of CO₂ and O₂ in the spectral region between 1250cm^-1 and 1680cm^-1. The aim is to perform temperature and concentration measurements in a typical hydrocarbon-air...

master thesis 2021

document

Coulomb Blockade Thermometry Beyond the Universal Regime

Yurttagul, N.F. (author), Sarsby, M. (author), Geresdi, A. (author)

The charge localization of single electrons on mesoscopic metallic islands leads to a suppression of the electrical current, known as the Coulomb blockade. When this correction is small, it enables primary electron thermometry, as it was first demonstrated by Pekola et al. (Phys Rev Lett 73:2903, 1994). However, in the low temperature limit,...

journal article 2021

document

Cascaded coherent anti-Stokes Raman scattering for high-sensitivity number density determination in the gas phase

Klyukin, Dmitry (author), Mazza, F. (author), Castellanos, Leonardo (author), Bohlin, G.A. (author)

Cascaded coherent anti-Stokes Raman scattering (CARS) signals can be efficiently generated from CARS signals when propagating collinearly with the pump/Stokes and probe beams. This effect can be seen as the CARS beam acting as the probe beam and being inelastically scattered a ‘second time’ from the Raman coherence induced along the focus of...

journal article 2021

document

Mr thermometry accuracy and prospective imaging-based patient selection in mr-guided hyperthermia treatment for locally advanced cervical cancer

Vilasboas-Ribeiro, Iva (author), Curto, Sergio (author), van Rhoon, G.C. (author), Franckena, Martine (author), Paulides, Margarethus M. (author)

The efficacy of a hyperthermia treatment depends on the delivery of well-controlled heating; hence, accurate temperature monitoring is essential for ensuring effective treatment. For deep pelvic hyperthermia, there are no comprehensive and systematic reports on MR thermometry. Moreover, data inclusion generally lacks objective selection...

journal article 2021

document

Passive Deep Ocean Thermometry using Hydroacoustic Signals from Submarine Earthquakes

Morandini, Ludovic (author)

Measuring temperature variations of the deep ocean is necessary to evaluate the heat flux between the atmosphere and the hydrosphere and thus calibrate climate change models. In the last two decades a passive alternative to profiling oceanographic floats has emerged: hydroacoustic thermometry. This method consists of using the oceanic ambient...

master thesis 2020

document

Fully Integrated CMOS Noise Thermometer

Kaandorp, Dennis (author)

Temperature sensors are integrated into virtually all electronic devices. Unfortunately, the accuracy of commonly used temperature sensors greatly deteriorates in more advanced CMOS processes, thus requiring a certain amount of calibration. Thermal noise thermometry is a highly accurate niche temperature sensing method. It employs the thermal...

master thesis 2020

document

Single-shot CARS imaging of near-wall turbulent reacting flows

El Sioufy, Karim (author)

This master thesis investigates the assessment of Flame-Wall Interaction using 1D broadband RCARS thermometry. Flame-Wall Interactions (FWI) have been shown to adversely effect combustion processes in terms of both efficiency and maximum performance. Heat and momentum losses cause incomplete combustion and allow for unburnt hydrocarbons (UHCs)...

master thesis 2020

document

Coherent Raman imaging thermometry with in-situ referencing of the impulsive excitation efficiency

Mazza, F. (author), Castellanos, Leonardo (author), Klyukin, Dmitry (author), Bohlin, G.A. (author)

Simultaneous detection of resonant and non-resonant femtosecond/picosecond coherent anti-Stokes Raman spectroscopy (CARS) signals has been developed as a viable technique to provide in-situ referencing of the impulsive excitation efficiency for temperature assessments in flames. In the framework of CARS thermometry, the occurrence of both a...

journal article 2020

document

Clinical performance and future potential of magnetic resonance thermometry in hyperthermia

Feddersen, Theresa V. (author), Hernandez-Tamames, J.A. (author), Franckena, Martine (author), van Rhoon, G.C. (author), Paulides, Margarethus M. (author)

Hyperthermia treatments in the clinic rely on accurate temperature measurements to guide treatments and evaluate clinical outcome. Currently, magnetic resonance thermometry (MRT) is the only clinical option to non-invasively measure 3D temperature distributions. In this review, we evaluate the status quo and emerging approaches in this...

review 2020

document

Calibrated quantum thermometry in cavity optomechanics

Chowdhury, A. (author), Vezio, P. (author), Bonaldi, M. (author), Borrielli, A. (author), Marino, F. (author), Morana, B. (author), Pandraud, G. (author), Sarro, Pasqualina M (author), Serra, E. (author)

Cavity optomechanics has achieved the major breakthrough of the preparation and observation of macroscopic mechanical oscillators in non-classical states. The development of reliable indicators of the oscillator properties in these conditions is important also for applications to quantum technologies. We compare two procedures to infer the...

journal article 2019