Short-term interactions between Staphylococcus aureus and Pseudomonas aeruginosa

Short-term interactions between Staphylococcus aureus and Pseudomonas aeruginosa: BEP Report

van der Poel, Jenneke (TU Delft Electrical Engineering, Mathematics and Computer Science)

Idema, T. (mentor)
Dubbeldam, J.L.A. (mentor)
Zwanikken, J.W. (graduation committee)
Gijswijt, Dion (graduation committee)

Delft University of Technology

Applied Mathematics

2024-02-02

Staphylococcus aureus and Pseudomonas aeruginosa are two species of bacteria that are involved in numerous conditions, including lung infections and chronic wound infections. The aim of this project was to study the short-term interactions that occur when P. aeruginosa first encounters an established S. aureus colony, which it then seeks to break apart whilst mixing with S. aureus. Limoli et al. have studied these interactions using experiments, and have thus identified several key aspects involved in these interactions, such as the mechanisms that P. aeruginosa employs to approach the S. aureus colony. The means by which we intended to study interactions between S. aureus and P. aeruginosa is a model that was made by previous members of the Idema group and that was based on the experiments by Limoli et al. In this report, we discuss this model and the biological background relevant to it. We also document the problems that we encountered while trying to run simulations using an existing implementation of this model.

bacteria
modelling
simulation

http://resolver.tudelft.nl/uuid:b76a158a-be59-47eb-80e6-f3b1498b0b6d

Student theses

bachelor thesis

© 2024 Jenneke van der Poel